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Creating a library of random transposon mutants in Leptospira

Generation of a random transposon mutant library is advantageous in Leptospira as site directed mutagenesis remains a challenge, especially in pathogenic species. This procedure is typically completed by transformation of Leptospira with a Himar1 containing plasmid via conjugation with Escherichia c...

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Bibliografiske detaljer
Udgivet i:Methods Mol Biol
Main Authors: Pappas, Christopher J., Xu, Hui, Motaleb, Md A.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473121/
https://ncbi.nlm.nih.gov/pubmed/32632861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-0716-0459-5_8
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