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Identification of a mutant locus by noncomplementation of a transposon insertion library in Saccharomyces cerevisiae.

We describe a new approach for identifying the gene corresponding to a mutation in Saccharomyces cerevisiae. A library of mTn-lacZ/LEU2 insertions is tested for failure to complement the mutation, and the noncomplementing insertion is used to obtain sequence. This approach offers an alternative to c...

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Detalhes bibliográficos
Main Authors: Wiatrowski, H A, Carlson, M
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461749/
https://ncbi.nlm.nih.gov/pubmed/11514465
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