Heme Induces IL-6 and Cardiac Hypertrophy Genes Transcripts in Sickle Cell Mice

Emerging data indicate that free heme promotes inflammation in many different disease settings, including in sickle cell disease (SCD). Although free heme, proinflammatory cytokines, and cardiac hypertrophy are co-existing features of SCD, no mechanistic links between these features have been demons...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Immunol
Prif Awduron: Gbotosho, Oluwabukola T., Kapetanaki, Maria G., Ghosh, Samit, Villanueva, Flordeliza S., Ofori-Acquah, Solomon F., Kato, Gregory J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Immunology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473032/
https://ncbi.nlm.nih.gov/pubmed/32973791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01910
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