Heme Induces IL-6 and Cardiac Hypertrophy Genes Transcripts in Sickle Cell Mice

Emerging data indicate that free heme promotes inflammation in many different disease settings, including in sickle cell disease (SCD). Although free heme, proinflammatory cytokines, and cardiac hypertrophy are co-existing features of SCD, no mechanistic links between these features have been demons...

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Bibliografski detalji
Izdano u:Front Immunol
Glavni autori: Gbotosho, Oluwabukola T., Kapetanaki, Maria G., Ghosh, Samit, Villanueva, Flordeliza S., Ofori-Acquah, Solomon F., Kato, Gregory J.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Immunology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473032/
https://ncbi.nlm.nih.gov/pubmed/32973791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01910
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