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Amphotericin B Specifically Induces the Two-Component System LnrJK: Development of a Novel Whole-Cell Biosensor for the Detection of Amphotericin-Like Polyenes

The rise of drug-resistant fungal pathogens urges for the development of new tools for the discovery of novel antifungal compounds. Polyene antibiotics are potent agents against fungal infections in humans and animals. They inhibit the growth of fungal cells by binding to sterols in the cytoplasmic...

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Bibliografske podrobnosti
izdano v:Front Microbiol
Main Authors: Revilla-Guarinos, Ainhoa, Dürr, Franziska, Popp, Philipp F., Döring, Maximilian, Mascher, Thorsten
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472640/
https://ncbi.nlm.nih.gov/pubmed/32973732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.02022
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