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Amphotericin B Specifically Induces the Two-Component System LnrJK: Development of a Novel Whole-Cell Biosensor for the Detection of Amphotericin-Like Polyenes

The rise of drug-resistant fungal pathogens urges for the development of new tools for the discovery of novel antifungal compounds. Polyene antibiotics are potent agents against fungal infections in humans and animals. They inhibit the growth of fungal cells by binding to sterols in the cytoplasmic...

詳細記述

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書誌詳細
出版年:Front Microbiol
主要な著者: Revilla-Guarinos, Ainhoa, Dürr, Franziska, Popp, Philipp F., Döring, Maximilian, Mascher, Thorsten
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472640/
https://ncbi.nlm.nih.gov/pubmed/32973732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.02022
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