Amphotericin B Specifically Induces the Two-Component System LnrJK: Development of a Novel Whole-Cell Biosensor for the Detection of Amphotericin-Like Polyenes

The rise of drug-resistant fungal pathogens urges for the development of new tools for the discovery of novel antifungal compounds. Polyene antibiotics are potent agents against fungal infections in humans and animals. They inhibit the growth of fungal cells by binding to sterols in the cytoplasmic...

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Dades bibliogràfiques
Publicat a:Front Microbiol
Autors principals: Revilla-Guarinos, Ainhoa, Dürr, Franziska, Popp, Philipp F., Döring, Maximilian, Mascher, Thorsten
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472640/
https://ncbi.nlm.nih.gov/pubmed/32973732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.02022
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