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Development of a novel heterologous β-lactam-specific whole-cell biosensor in Bacillus subtilis

BACKGROUND: Whole-cell biosensors are a powerful and easy-to-use screening tool for the fast and sensitive detection of chemical compounds, such as antibiotics. β-Lactams still represent one of the most important antibiotic groups in therapeutic use. They interfere with late stages of the bacterial...

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Détails bibliographiques
Publié dans:J Biol Eng
Auteurs principaux: Lautenschläger, Nina, Popp, Philipp F., Mascher, Thorsten
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394692/
https://ncbi.nlm.nih.gov/pubmed/32765644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-020-00243-4
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