ASC modulates HIF-1α stability and induces cell mobility in OSCC

High-level expression of ASC (Apoptosis-associated speck-like protein containing a CARD) leads to lymph node metastasis in OSCC, but the underlying mechanism remains unclear. Here, we show that HIF-1α participates in ASC-induced metastasis. We identified 195 cell-motion-associated genes that were hi...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wu, Chi-Sheng, Chang, Ian Yi-Feng, Hung, Jui-lung, Liao, Wei-Chao, Lai, Yi-Ru, Chang, Kai-Ping, Li, Hsin-Pai, Chang, Yu-Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471912/
https://ncbi.nlm.nih.gov/pubmed/32883954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02927-7
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