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Sterically stabilized liposomes targeting P21 (RAC1) activated kinase-1 and secreted phospholipase A(2) suppress prostate cancer growth and metastasis
Metastatic prostate cancer (PCa) has a very high mortality rate in men, in Western countries and lacks reliable treatment. The advanced-stage PCa cells overexpress P21 (RAC1) activated kinase-1 (PAK1) and secreted phospholipase A(2) (sPLA(2)) suggesting the potential utility of pharmacologically tar...
Gespeichert in:
| Veröffentlicht in: | Oncol Lett |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
D.A. Spandidos
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7471734/ https://ncbi.nlm.nih.gov/pubmed/32934746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.12040 |
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