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Liposomal-mediated delivery of the p21 activated kinase-1 (PAK-1) inhibitorIPA-3limits prostate tumor growth in vivo
P21 activated kinases-1 (PAK-1)is implicated in various diseases. It is inhibited by thesmall molecule ‘Inhibitor targeting PAK1 activation-3’ (IPA-3), which is highly specific but metabolically unstable. To address this limitation we encapsulatedIPA-3 in sterically stabilized liposomes (SSL). SSL-I...
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| Publicado no: | Nanomedicine |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889517/ https://ncbi.nlm.nih.gov/pubmed/26949163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2016.01.003 |
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