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The Selective Peroxisome Proliferator‐Activated Receptor Gamma Modulator CHS‐131 Improves Liver Histopathology and Metabolism in a Mouse Model of Obesity and Nonalcoholic Steatohepatitis

CHS‐131 is a selective peroxisome proliferator‐activated receptor gamma modulator with antidiabetic effects and less fluid retention and weight gain compared to thiazolidinediones in phase II clinical trials. We investigated the effects of CHS‐131 on metabolic parameters and liver histopathology in...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Hepatol Commun
Päätekijät: Perakakis, Nikolaos, Joshi, Aditya, Peradze, Natia, Stefanakis, Konstantinos, Li, Georgia, Feigh, Michael, Veidal, Sanne Skovgard, Rosen, Glenn, Fleming, Michael, Mantzoros, Christos S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7471426/
https://ncbi.nlm.nih.gov/pubmed/32923834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1558
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