Disease Progression and Pharmacological Intervention in a Nutrient-Deficient Rat Model of Nonalcoholic Steatohepatitis

BACKGROUND: There is a marked need for improved animal models of nonalcoholic steatohepatitis (NASH) to facilitate the development of more efficacious drug therapies for the disease. METHODS: Here, we investigated the development of fibrotic NASH in male Wistar rats fed a choline-deficient l-amino a...

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Publicat a:Dig Dis Sci
Autors principals: Tølbøl, Kirstine S., Stierstorfer, Birgit, Rippmann, Jörg F., Veidal, Sanne S., Rigbolt, Kristoffer T. G., Schönberger, Tanja, Gillum, Matthew P., Hansen, Henrik H., Vrang, Niels, Jelsing, Jacob, Feigh, Michael, Broermann, Andre
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2018
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548202/
https://ncbi.nlm.nih.gov/pubmed/30511198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-018-5395-7
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