Disease Progression and Pharmacological Intervention in a Nutrient-Deficient Rat Model of Nonalcoholic Steatohepatitis

BACKGROUND: There is a marked need for improved animal models of nonalcoholic steatohepatitis (NASH) to facilitate the development of more efficacious drug therapies for the disease. METHODS: Here, we investigated the development of fibrotic NASH in male Wistar rats fed a choline-deficient l-amino a...

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Detalhes bibliográficos
Publicado no:Dig Dis Sci
Main Authors: Tølbøl, Kirstine S., Stierstorfer, Birgit, Rippmann, Jörg F., Veidal, Sanne S., Rigbolt, Kristoffer T. G., Schönberger, Tanja, Gillum, Matthew P., Hansen, Henrik H., Vrang, Niels, Jelsing, Jacob, Feigh, Michael, Broermann, Andre
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548202/
https://ncbi.nlm.nih.gov/pubmed/30511198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-018-5395-7
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