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Leptin alters energy intake and fat mass but not energy expenditure in lean subjects

Based on studies in mice, leptin was expected to decrease body weight in obese individuals. However, the majority of the obese are hyperleptinemic and do not respond to leptin treatment, suggesting the presence of leptin tolerance and questioning the role of leptin as regulator of energy balance in...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Chrysafi, Pavlina, Perakakis, Nikolaos, Farr, Olivia M., Stefanakis, Konstantinos, Peradze, Natia, Sala-Vila, Aleix, Mantzoros, Christos S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553922/
https://ncbi.nlm.nih.gov/pubmed/33051459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18885-9
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