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Anti-inflammatory functions of the glucocorticoid receptor require DNA binding

The glucocorticoid receptor is an important immunosuppressive drug target and metabolic regulator that acts as a ligand-gated transcription factor. Generally, GR’s anti-inflammatory effects are attributed to the silencing of inflammatory genes, while its adverse effects are ascribed to the upregulat...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Escoter-Torres, Laura, Greulich, Franziska, Quagliarini, Fabiana, Wierer, Michael, Uhlenhaut, Nina Henriette
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470971/
https://ncbi.nlm.nih.gov/pubmed/32619221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa565
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