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The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers
Glucocorticoids (GCs) are effective anti-inflammatory drugs; yet, their mechanisms of action are poorly understood. GCs bind to the glucocorticoid receptor (GR), a ligand-gated transcription factor controlling gene expression in numerous cell types. Here, we characterize GR’s protein interactome and...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7873837/ https://ncbi.nlm.nih.gov/pubmed/33567280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108742 |
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