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Impact of 5-formylcytosine on the melting kinetics of DNA by (1)H NMR chemical exchange

5-Formylcytosine (5fC) is a chemically edited, naturally occurring nucleobase which appears in the context of modified DNA strands. The understanding of the impact of 5fC on dsDNA physical properties is to date limited. In this work, we applied temperature-dependent (1)H Chemical Exchange Saturation...

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Publicat a:Nucleic Acids Res
Autors principals: Dubini, Romeo C A, Schön, Alexander, Müller, Markus, Carell, Thomas, Rovó, Petra
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470965/
https://ncbi.nlm.nih.gov/pubmed/32652019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa589
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