Dnmt1 binds and represses genomic retroelements via DNA methylation in mouse early embryos

Genome-wide passive DNA demethylation in cleavage-stage mouse embryos is related to the cytoplasmic localization of the maintenance methyltransferase DNMT1. However, recent studies provided evidences of the nuclear localization of DNMT1 and its contribution to the maintenance of methylation levels o...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Min, Byungkuk, Park, Jung Sun, Jeong, Young Sun, Jeon, Kyuheum, Kang, Yong-Kook
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470951/
https://ncbi.nlm.nih.gov/pubmed/32667642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa584
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