CASC3 promotes transcriptome-wide activation of nonsense-mediated decay by the exon junction complex

The exon junction complex (EJC) is an essential constituent and regulator of spliced messenger ribonucleoprotein particles (mRNPs) in metazoans. As a core component of the EJC, CASC3 was described to be pivotal for EJC-dependent nuclear and cytoplasmic processes. However, recent evidence suggests th...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Gerbracht, Jennifer V, Boehm, Volker, Britto-Borges, Thiago, Kallabis, Sebastian, Wiederstein, Janica L, Ciriello, Simona, Aschemeier, Dominik U, Krüger, Marcus, Frese, Christian K, Altmüller, Janine, Dieterich, Christoph, Gehring, Niels H
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
RNA and RNA-protein complexes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470949/
https://ncbi.nlm.nih.gov/pubmed/32621609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa564
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