Dual roles of yeast Rad51 N-terminal domain in repairing DNA double-strand breaks

Highly toxic DNA double-strand breaks (DSBs) readily trigger the DNA damage response (DDR) in cells, which delays cell cycle progression to ensure proper DSB repair. In Saccharomyces cerevisiae, mitotic S phase (20–30 min) is lengthened upon DNA damage. During meiosis, Spo11-induced DSB onset and re...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Woo, Tai-Ting, Chuang, Chi-Ning, Higashide, Mika, Shinohara, Akira, Wang, Ting-Fang
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Genome Integrity, Repair and Replication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470947/
https://ncbi.nlm.nih.gov/pubmed/32652040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa587
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