Distinct Temporal Structure of Nicotinic ACh Receptor Activation Determines Responses of VTA Neurons to Endogenous ACh and Nicotine

The addictive component of tobacco, nicotine, acts via nicotinic acetylcholine receptors (nAChRs). The β2 subunit-containing nAChRs (β2-nAChRs) play a crucial role in the rewarding properties of nicotine and are particularly densely expressed in the mesolimbic dopamine (DA) system. Specifically, nAC...

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Bibliografske podrobnosti
izdano v:eNeuro
Main Authors: Morozova, Ekaterina, Faure, Philippe, Gutkin, Boris, Lapish, Christoper, Kuznetsov, Alexey
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2020
Teme:
Research Article: New Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470928/
https://ncbi.nlm.nih.gov/pubmed/32737187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0418-19.2020
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