Distinct Temporal Structure of Nicotinic ACh Receptor Activation Determines Responses of VTA Neurons to Endogenous ACh and Nicotine

The addictive component of tobacco, nicotine, acts via nicotinic acetylcholine receptors (nAChRs). The β2 subunit-containing nAChRs (β2-nAChRs) play a crucial role in the rewarding properties of nicotine and are particularly densely expressed in the mesolimbic dopamine (DA) system. Specifically, nAC...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Morozova, Ekaterina, Faure, Philippe, Gutkin, Boris, Lapish, Christoper, Kuznetsov, Alexey
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Research Article: New Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470928/
https://ncbi.nlm.nih.gov/pubmed/32737187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0418-19.2020
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