Detection of NRG1 gene fusions in solid tumors

BACKGROUND: NRG1 gene fusions are rare but potentially actionable oncogenic drivers present in some solid tumors. Details regarding the incidence of these gene rearrangements are lacking. Here, we assessed the incidence of NRG1 fusions across multiple tumor types and described fusion partners. METHO...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Jonna, Sushma, Feldman, Rebecca A., Swensen, Jeffrey, Gatalica, Zoran, Korn, Wolfgang M., Borghaei, Hossein, Ma, Patrick C., Nieva, Jorge, Spira, Alexander, Vanderwalde, Ari, Wozniak, Antoinette, Kim, Edward S., Liu, Stephen V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470623/
https://ncbi.nlm.nih.gov/pubmed/30988082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-0160
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