Efficient synthesis, biological evaluation, and docking study of isatin based derivatives as caspase inhibitors

In this paper, a new series of isatin-sulphonamide based derivatives were designed, synthesised and evaluated as caspase inhibitors. The compounds containing 1-(pyrrolidinyl)sulphonyl and 2-(phenoxymethyl)pyrrolidin-1-yl)sulphonyl substitution at C5 position of isatin core exhibited better results c...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Enzyme Inhib Med Chem
Päätekijät: Firoozpour, Loghman, Gao, Lixin, Moghimi, Setareh, Pasalar, Parvin, Davoodi, Jamshid, Wang, Ming-Wei, Rezaei, Zahra, Dadgar, Armin, Yahyavi, Hoda, Amanlou, Massoud, Foroumadi, Alireza
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2020
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470124/
https://ncbi.nlm.nih.gov/pubmed/32842789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1809388
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