Design, synthesis, docking study and cytotoxic activity evaluation of some novel letrozole analogs

BACKGROUND: Breast cancer is the most common type of female cancer. One class of hormonal therapy for breast cancer drugs -non steroidal aromatase inhibitors- are triazole analogues. In this work, some derivatives of these drugs was designed and synthesized. All synthesized compounds were evaluated...

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Detalhes bibliográficos
Publicado no:Daru
Main Authors: Vosooghi, Mohsen, Firoozpour, Loghman, Rodaki, Abolfazl, Pordeli, Mahboobeh, Safavi, Maliheh, Ardestani, Sussan K, Dadgar, Armin, Asadipour, Ali, Moshafi, Mohammad Hassan, Foroumadi, Alireza
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284924/
https://ncbi.nlm.nih.gov/pubmed/25539909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40199-014-0083-4
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