Novel N-2-(Furyl)-2-(chlorobenzyloxyimino) Ethyl Piperazinyl Quinolones: Synthesis, Cytotoxic Evaluation and Structure-Activity Relationship

Quinolone antibacterials are one of the most important classes of pharmacological agents known as potent inhibitors of bacterial DNA gyrase and topoisomerase IV that efficiently inhibit DNA replication and transcription by generating several double-stranded DNA break. Some quinolone derivatives demo...

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Detalhes bibliográficos
Publicado no:Iran J Pharm Res
Main Authors: Mohammadhosseini, Negar, Pordeli, Mahboobeh, Safavi, Maliheh, Firoozpour, Loghman, Amin, Fatame, Kabudanian Ardestani, Sussan, Edraki, Najmeh, Shafiee, Abbas, Foroumadi, Alireza
Formato: Artigo
Idioma:Inglês
Publicado em: Shaheed Beheshti University of Medical Sciences 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673937/
https://ncbi.nlm.nih.gov/pubmed/26664376
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