A carregar...

Synthesis and structure-activity relationships of novel 5-(hydroxamic acid)methyl oxazolidinone derivatives as 5-lipoxygenase inhibitors

Oxazolidinone hydroxamic acid derivatives were synthesised and evaluated for inhibitory activity against leukotriene (LT) biosynthesis in three in vitro cell-based test systems and on direct inhibition of recombinant human 5-lipoxygenase (5-LO). Thirteen of the 19 compounds synthesised were consider...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Phillips, Oludotun A., Bosso, Mira A., Ezeamuzie, Charles I.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470027/
https://ncbi.nlm.nih.gov/pubmed/32635785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1786082
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!