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Novel Actions of Oxazolidinones: In vitro Screening of a Triazolyloxazolidinone for Anticonvulsant Activity

OBJECTIVE: To test the hypothesis that a triazolyloxazolidinone (PH084) has anticonvulsant activity by examining its effects on in vitro seizure models in the rat hippocampus. MATERIALS AND METHODS: Whole-cell synaptic currents, action potentials and extracellular population spikes (PS) were recorde...

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Detalhes bibliográficos
Publicado no:Med Princ Pract
Main Authors: Kombian, Samuel B., Phillips, Oludotun A.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586748/
https://ncbi.nlm.nih.gov/pubmed/23257573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000346005
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