Evaluation of Anticonvulsant Actions of Dibromophenyl Enaminones Using In Vitro and In Vivo Seizure Models

Epilepsy and other seizure disorders are not adequately managed with currently available drugs. We recently synthesized a series of dibromophenyl enaminones and demonstrated that AK6 and E249 were equipotent to previous analogs but more efficacious in suppressing neuronal excitation. Here we examine...

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Detaylı Bibliyografya
Asıl Yazarlar: Qaddoumi, Mohamed G., Ananthalakshmi, Kethireddy V. V., Phillips, Oludotun A., Edafiogho, Ivan O., Kombian, Samuel B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063795/
https://ncbi.nlm.nih.gov/pubmed/24945912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099770
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