Targeting Novel Sodium Iodide Symporter Interactors ADP-Ribosylation Factor 4 and Valosin-Containing Protein Enhances Radioiodine Uptake

The sodium iodide symporter (NIS) is required for iodide uptake, which facilitates thyroid hormone biosynthesis. NIS has been exploited for over 75 years in ablative radioiodine (RAI) treatment of thyroid cancer, where its ability to transport radioisotopes depends on its localization to the plasma...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Res
Egile Nagusiak: Fletcher, Alice, Read, Martin L., Thornton, Caitlin E.M., Larner, Dean P., Poole, Vikki L., Brookes, Katie, Nieto, Hannah R., Alshahrani, Mohammed, Thompson, Rebecca J., Lavery, Gareth G., Landa, Iñigo, Fagin, James A., Campbell, Moray J., Boelaert, Kristien, Turnell, Andrew S., Smith, Vicki E., McCabe, Christopher J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470018/
https://ncbi.nlm.nih.gov/pubmed/31672844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-1957
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