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The Effect of Tanespimycin (17-AAG) on Radioiodine Accumulation in Sodium-Iodide Symporter Expressing Cells

PURPOSE: The heat shock protein 90 inhibitor, tanespimycin, is an anticancer agent known to increase iodine accumulation in normal and cancerous thyroid cells. Iodine accumulation is regulated by membrane proteins such as sodium iodide symporter (NIS) and pendrin (PDS), and thus we attempted to char...

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Detalhes bibliográficos
Main Authors: Yu, Kyoung Hyun, Youn, Hyewon, Song, Myung Geun, Lee, Dong Soo, Chung, June-Key
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043063/
https://ncbi.nlm.nih.gov/pubmed/24900070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13139-012-0158-4
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