Glycosylation of Sodium/Iodide Symporter (NIS) Regulates Its Membrane Translocation and Radioiodine Uptake

PURPOSE: Human sodium/iodide symporter (hNIS) protein is a membrane glycoprotein that transports iodide ions into thyroid cells. The function of this membrane protein is closely regulated by post-translational glycosylation. In this study, we measured glycosylation-mediated changes in subcellular lo...

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Bibliographic Details
Published in:PLoS One
Main Authors: Chung, Taemoon, Youn, Hyewon, Yeom, Chan Joo, Kang, Keon Wook, Chung, June-Key
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658105/
https://ncbi.nlm.nih.gov/pubmed/26599396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142984
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