The Effect of Tanespimycin (17-AAG) on Radioiodine Accumulation in Sodium-Iodide Symporter Expressing Cells

PURPOSE: The heat shock protein 90 inhibitor, tanespimycin, is an anticancer agent known to increase iodine accumulation in normal and cancerous thyroid cells. Iodine accumulation is regulated by membrane proteins such as sodium iodide symporter (NIS) and pendrin (PDS), and thus we attempted to char...

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Bibliografiske detaljer
Main Authors: Yu, Kyoung Hyun, Youn, Hyewon, Song, Myung Geun, Lee, Dong Soo, Chung, June-Key
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2012
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043063/
https://ncbi.nlm.nih.gov/pubmed/24900070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13139-012-0158-4
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