A novel mechanism of sodium iodide symporter repression in differentiated thyroid cancer

Differentiated thyroid cancers and their metastases frequently exhibit reduced iodide uptake, impacting on the efficacy of radioiodine ablation therapy. PTTG binding factor (PBF) is a proto-oncogene implicated in the pathogenesis of thyroid cancer. We recently reported that PBF inhibits iodide uptak...

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Detaylı Bibliyografya
Asıl Yazarlar: Smith, Vicki E., Read, Martin L., Turnell, Andrew S., Watkins, Rachel J., Watkinson, John C., Lewy, Greg D., Fong, Jim C. W., James, Sally R., Eggo, Margaret C., Boelaert, Kristien, Franklyn, Jayne A., McCabe, Christopher J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Company of Biologists 2009
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736868/
https://ncbi.nlm.nih.gov/pubmed/19706688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.045427
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