A novel mechanism of sodium iodide symporter repression in differentiated thyroid cancer

Differentiated thyroid cancers and their metastases frequently exhibit reduced iodide uptake, impacting on the efficacy of radioiodine ablation therapy. PTTG binding factor (PBF) is a proto-oncogene implicated in the pathogenesis of thyroid cancer. We recently reported that PBF inhibits iodide uptak...

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Detalhes bibliográficos
Main Authors: Smith, Vicki E., Read, Martin L., Turnell, Andrew S., Watkins, Rachel J., Watkinson, John C., Lewy, Greg D., Fong, Jim C. W., James, Sally R., Eggo, Margaret C., Boelaert, Kristien, Franklyn, Jayne A., McCabe, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736868/
https://ncbi.nlm.nih.gov/pubmed/19706688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.045427
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