Proto-oncogene PBF/PTTG1IP regulates thyroid cell growth and represses radioiodide treatment

PTTG Binding Factor (PBF or PTTG1IP) is a little characterised proto-oncogene that has been implicated in the etiology of breast and thyroid tumors. In this study, we created a murine transgenic model to target PBF expression to the thyroid gland (PBF-Tg mice) and found that these mice exhibited nor...

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Detalhes bibliográficos
Main Authors: Read, Martin L., Lewy, Greg D., Fong, Jim C.W., Sharma, Neil, Seed, Robert I., Smith, Vicki E., Gentilin, Erica, Warfield, Adrian, Eggo, Margaret C., Knauf, Jeffrey A., Leadbeater, Wendy E., Watkinson, John C., Franklyn, Jayne A., Boelaert, Kristien, McCabe, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184940/
https://ncbi.nlm.nih.gov/pubmed/21844185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-0720
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