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Pro-invasive Effect of Proto-oncogene PBF Is Modulated by an Interaction with Cortactin

CONTEXT: Metastatic disease is responsible for the majority of endocrine cancer deaths. New therapeutic targets are urgently needed to improve patient survival rates. OBJECTIVE: The proto-oncogene PTTG1-binding factor (PBF/PTTG1IP) is overexpressed in multiple endocrine cancers and circumstantially...

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Vydáno v:J Clin Endocrinol Metab
Hlavní autoři: Watkins, Rachel J., Imruetaicharoenchoke, Waraporn, Read, Martin L., Sharma, Neil, Poole, Vikki L., Gentilin, Erica, Bansal, Sukhchain, Bosseboeuf, Emy, Fletcher, Rachel, Nieto, Hannah R., Mallick, Ujjal, Hackshaw, Allan, Mehanna, Hisham, Boelaert, Kristien, Smith, Vicki E., McCabe, Christopher J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155689/
https://ncbi.nlm.nih.gov/pubmed/27603901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-1932
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