Pro-invasive Effect of Proto-oncogene PBF Is Modulated by an Interaction with Cortactin

CONTEXT: Metastatic disease is responsible for the majority of endocrine cancer deaths. New therapeutic targets are urgently needed to improve patient survival rates. OBJECTIVE: The proto-oncogene PTTG1-binding factor (PBF/PTTG1IP) is overexpressed in multiple endocrine cancers and circumstantially...

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Pubblicato in:J Clin Endocrinol Metab
Autori principali: Watkins, Rachel J., Imruetaicharoenchoke, Waraporn, Read, Martin L., Sharma, Neil, Poole, Vikki L., Gentilin, Erica, Bansal, Sukhchain, Bosseboeuf, Emy, Fletcher, Rachel, Nieto, Hannah R., Mallick, Ujjal, Hackshaw, Allan, Mehanna, Hisham, Boelaert, Kristien, Smith, Vicki E., McCabe, Christopher J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2016
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155689/
https://ncbi.nlm.nih.gov/pubmed/27603901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-1932
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