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Pro-invasive Effect of Proto-oncogene PBF Is Modulated by an Interaction with Cortactin

CONTEXT: Metastatic disease is responsible for the majority of endocrine cancer deaths. New therapeutic targets are urgently needed to improve patient survival rates. OBJECTIVE: The proto-oncogene PTTG1-binding factor (PBF/PTTG1IP) is overexpressed in multiple endocrine cancers and circumstantially...

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Detalles Bibliográficos
Publicado en:J Clin Endocrinol Metab
Autores principales: Watkins, Rachel J., Imruetaicharoenchoke, Waraporn, Read, Martin L., Sharma, Neil, Poole, Vikki L., Gentilin, Erica, Bansal, Sukhchain, Bosseboeuf, Emy, Fletcher, Rachel, Nieto, Hannah R., Mallick, Ujjal, Hackshaw, Allan, Mehanna, Hisham, Boelaert, Kristien, Smith, Vicki E., McCabe, Christopher J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155689/
https://ncbi.nlm.nih.gov/pubmed/27603901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-1932
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