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In vitro Models of the Blood-Brain Barrier: Building in physiological complexity
Development of brain therapeutics is significantly hampered by the presence of the blood-brain barrier (BBB). Classical transwell models are able to recapitulate many important aspects of drug transport across the BBB, but are not completely predictive of in vivo brain uptake. Species differences fu...
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| Опубликовано в: : | Curr Opin Chem Eng |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7469950/ https://ncbi.nlm.nih.gov/pubmed/32905326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coche.2020.07.002 |
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