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Transcriptional Responses of In Vitro Blood–Brain Barrier Models to Shear Stress

Endothelial cells throughout the body sense blood flow, eliciting transcriptional and phenotypic responses. The brain endothelium, known as the blood–brain barrier (BBB), possesses unique barrier and transport properties, which are in part regulated by blood flow. We utilized RNA sequencing to analy...

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Autors principals: Koji L. Foreman, Benjamin D. Gastfriend, Moriah E. Katt, Sean P. Palecek, Eric V. Shusta
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2025-01-01
Col·lecció:Biomolecules
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Accés en línia:https://www.mdpi.com/2218-273X/15/2/193
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