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In vitro Models of the Blood-Brain Barrier: Building in physiological complexity
Development of brain therapeutics is significantly hampered by the presence of the blood-brain barrier (BBB). Classical transwell models are able to recapitulate many important aspects of drug transport across the BBB, but are not completely predictive of in vivo brain uptake. Species differences fu...
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| Pubblicato in: | Curr Opin Chem Eng |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7469950/ https://ncbi.nlm.nih.gov/pubmed/32905326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coche.2020.07.002 |
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