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GUIP1: a R package for dose escalation strategies in phase I cancer clinical trials

BACKGROUND: The main objective of phase I cancer clinical trials is to identify the maximum tolerated dose, usually defined as the highest dose associated with an acceptable level of severe toxicity during the first cycle of treatment. Several dose-escalation designs based on mathematical modeling o...

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Bibliografiske detaljer
Udgivet i:BMC Med Inform Decis Mak
Main Authors: Dinart, D., Fraisse, J., Tosi, D., Mauguen, A., Touraine, C., Gourgou, S., Le Deley, M. C., Bellera, C., Mollevi, C.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469913/
https://ncbi.nlm.nih.gov/pubmed/32580715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12911-020-01149-3
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