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GUIP1: a R package for dose escalation strategies in phase I cancer clinical trials

BACKGROUND: The main objective of phase I cancer clinical trials is to identify the maximum tolerated dose, usually defined as the highest dose associated with an acceptable level of severe toxicity during the first cycle of treatment. Several dose-escalation designs based on mathematical modeling o...

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Detalles Bibliográficos
Publicado en:BMC Med Inform Decis Mak
Main Authors: Dinart, D., Fraisse, J., Tosi, D., Mauguen, A., Touraine, C., Gourgou, S., Le Deley, M. C., Bellera, C., Mollevi, C.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469913/
https://ncbi.nlm.nih.gov/pubmed/32580715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12911-020-01149-3
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