miR-296-5p inhibits IL-1β-induced apoptosis and cartilage degradation in human chondrocytes by directly targeting TGF-β1/CTGF/p38MAPK pathway

Osteoarthritis (OA) is characterized by apoptosis of chondrocytes and an imbalance of extracellular matrix (ECM) synthesis and catabolism. Emerging evidence has demonstrated that miRNAs are involved in OA pathologies, but the role of miR-296-5p in OA remains unclear. The present study proposes to re...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Cao, Zhilin, Liu, Wenguang, Qu, Xiaoyi, Bi, Haiyong, Sun, Xiujiang, Yu, Qian, Cheng, Gong
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469671/
https://ncbi.nlm.nih.gov/pubmed/32378978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2020.1750813
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