miR-296-5p inhibits IL-1β-induced apoptosis and cartilage degradation in human chondrocytes by directly targeting TGF-β1/CTGF/p38MAPK pathway

Osteoarthritis (OA) is characterized by apoptosis of chondrocytes and an imbalance of extracellular matrix (ECM) synthesis and catabolism. Emerging evidence has demonstrated that miRNAs are involved in OA pathologies, but the role of miR-296-5p in OA remains unclear. The present study proposes to re...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Cycle
Auteurs principaux: Cao, Zhilin, Liu, Wenguang, Qu, Xiaoyi, Bi, Haiyong, Sun, Xiujiang, Yu, Qian, Cheng, Gong
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2020
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469671/
https://ncbi.nlm.nih.gov/pubmed/32378978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2020.1750813
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