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Selective autophagy inhibition through disruption of the PIK3C3-containing complex I
The PIK3C3/VPS34-containing phosphatidylinositol 3-kinase (PtdIns3K) initiation complex (complex I) is necessary for macroautophagy/autophagy initiation and is comprised of PIK3R4/VPS15-PIK3C3/VPS34-BECN1-ATG14, while the endosomal trafficking complex (complex II) is necessary for vesicle traffickin...
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| Udgivet i: | Autophagy |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7469636/ https://ncbi.nlm.nih.gov/pubmed/32619130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1786268 |
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