Caricamento...
Targeting tumor vulnerabilities associated with loss of heterozygosity
We show that N-acetyltransferase 2 (NAT2) loss of heterozygosity can be targeted in >4% of colorectal cancers with the use of a small molecule. We identify and describe the effect of a compound that impairs the growth of colorectal tumors with slow NAT2 activity by half when compared to wild-type...
Salvato in:
| Pubblicato in: | Mol Cell Oncol |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2020
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7469497/ https://ncbi.nlm.nih.gov/pubmed/32944621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1759390 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|