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Inhibition of γ-secretase in adipocytes leads to altered IL-6 secretion and adipose inflammation

Adipocyte-mediated inflammatory signalling has been proposed to alter adipose physiology in obesity and Type 2 diabetes mellitus. Novel targets for alteration of inflammatory signalling are needed to improve obesity-related outcomes. The γ-secretase enzyme complex has been suggested to play a role b...

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Bibliografiske detaljer
Udgivet i:Adipocyte
Main Authors: Sparling, David P., McCullough, Nile, Pajvani, Utpal, Humphrey, Mary Beth
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469479/
https://ncbi.nlm.nih.gov/pubmed/32603641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21623945.2020.1788235
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