Brown adipose tissue whitening leads to brown adipocyte death and adipose tissue inflammation

In mammals, white adipose tissue (WAT) stores and releases lipids, whereas brown adipose tissue (BAT) oxidizes lipids to fuel thermogenesis. In obese individuals, WAT undergoes profound changes; it expands, becomes dysfunctional, and develops a low-grade inflammatory state. Importantly, BAT content...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Kotzbeck, Petra, Giordano, Antonio, Mondini, Eleonora, Murano, Incoronata, Severi, Ilenia, Venema, Wiebe, Cecchini, Maria Paola, Kershaw, Erin E., Barbatelli, Giorgio, Haemmerle, Guenter, Zechner, Rudolf, Cinti, Saverio
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928436/
https://ncbi.nlm.nih.gov/pubmed/29599420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M079665
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