Brown adipose tissue whitening leads to brown adipocyte death and adipose tissue inflammation

In mammals, white adipose tissue (WAT) stores and releases lipids, whereas brown adipose tissue (BAT) oxidizes lipids to fuel thermogenesis. In obese individuals, WAT undergoes profound changes; it expands, becomes dysfunctional, and develops a low-grade inflammatory state. Importantly, BAT content...

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Vydáno v:J Lipid Res
Hlavní autoři: Kotzbeck, Petra, Giordano, Antonio, Mondini, Eleonora, Murano, Incoronata, Severi, Ilenia, Venema, Wiebe, Cecchini, Maria Paola, Kershaw, Erin E., Barbatelli, Giorgio, Haemmerle, Guenter, Zechner, Rudolf, Cinti, Saverio
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928436/
https://ncbi.nlm.nih.gov/pubmed/29599420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M079665
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