Brown adipose tissue whitening leads to brown adipocyte death and adipose tissue inflammation

In mammals, white adipose tissue (WAT) stores and releases lipids, whereas brown adipose tissue (BAT) oxidizes lipids to fuel thermogenesis. In obese individuals, WAT undergoes profound changes; it expands, becomes dysfunctional, and develops a low-grade inflammatory state. Importantly, BAT content...

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Bibliografiska uppgifter
I publikationen:J Lipid Res
Huvudupphovsmän: Kotzbeck, Petra, Giordano, Antonio, Mondini, Eleonora, Murano, Incoronata, Severi, Ilenia, Venema, Wiebe, Cecchini, Maria Paola, Kershaw, Erin E., Barbatelli, Giorgio, Haemmerle, Guenter, Zechner, Rudolf, Cinti, Saverio
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Biochemistry and Molecular Biology 2018
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928436/
https://ncbi.nlm.nih.gov/pubmed/29599420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M079665
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