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Fto-Deficiency Affects the Gene and MicroRNA Expression Involved in Brown Adipogenesis and Browning of White Adipose Tissue in Mice

Genetic variants in the fat mass- and obesity-associated gene Fto are linked to the onset of obesity in humans. The causal role of the FTO protein in obesity is supported by evidence obtained from transgenic mice; however, the underlying molecular pathways pertaining to the role of FTO in obesity ha...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Ronkainen, Justiina, Mondini, Eleonora, Cinti, Francesca, Cinti, Saverio, Sebért, Sylvain, Savolainen, Markku J., Salonurmi, Tuire
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133851/
https://ncbi.nlm.nih.gov/pubmed/27827997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17111851
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