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Hsp70:CHIP Ubiquitinates Dysfunctional but Not Native Neuronal NO Synthase
Heat shock protein (Hsp) 70 modulators are being developed to enhance the removal of toxic proteins in a variety of protein misfolding diseases. In the course of our studies on neuronal nitric oxide synthase (nNOS), a client of the Hsp90 and Hsp70 chaperone system, we have established that inactivat...
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| Publicat a: | Mol Pharmacol |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Pharmacology and Experimental Therapeutics
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7469249/ https://ncbi.nlm.nih.gov/pubmed/32591478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.120.119990 |
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