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Lipid droplets disrupt mechanosensing in human hepatocytes

Hepatocellular carcinoma (HCC) is the fourth-leading cause of cancer death in the world. Although most cases occur in stiff, cirrhotic livers, and stiffness is a significant risk factor, HCC can also arise in noncirrhotic livers in the setting of nonalcoholic fatty liver disease (NAFLD). We hypothes...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Chin, LiKang, Theise, Neil D., Loneker, Abigail E., Janmey, Paul A., Wells, Rebecca G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7468756/
https://ncbi.nlm.nih.gov/pubmed/32463334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00098.2020
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