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High Phosphate Induces and Klotho Attenuates Kidney Epithelial Senescence and Fibrosis
Cellular senescence is an irreversible cell growth arrest and is associated with aging and age-related diseases. High plasma phosphate (Pi) and deficiency of Klotho contribute to aging and kidney fibrosis, a pathological feature in the aging kidney and chronic kidney disease. This study examined the...
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| Gepubliceerd in: | Front Pharmacol |
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| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Frontiers Media S.A.
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7468469/ https://ncbi.nlm.nih.gov/pubmed/32973510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01273 |
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